Effect of Monoamine Oxidase Inhibitor on Developmental Mechanism in the Amphibian.
نویسندگان
چکیده
大鹿 英世 ・中井 健五 Accumulating evidence indicates that monoamine oxidase (MAO, 1.4.3.4) is essential to the metabolism of serotonin and catecholamines. Since these amines are substances of high biological activity and have been implicated in autonomic function, it becomes of great interest to see whether foetal or embryonic development is closely related to the metabolism of these biogenic amines. Therefore, evaluation of action of MAO inhibitor on animals in undeveloped stage may afford some clue as to the biological significance of the amines. The present paper deals with appearance of MAO in the larval stage of the amphibian and also with effect of MAO inhibitor on the developmental mechanism.
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عنوان ژورنال:
- Japanese journal of pharmacology
دوره 15 شماره
صفحات -
تاریخ انتشار 1965